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canertinib dihydrochloride  (TargetMol)


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    TargetMol canertinib dihydrochloride

    Canertinib Dihydrochloride, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/canertinib+dihydrochloride/Canertinib+dihydrochloride/pmc12718461-23-0-3
    Average 93 stars, based on 1 article reviews
    canertinib dihydrochloride - by Bioz Stars, 2026-10
    93/100 stars

    Images

    1) Product Images from "Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform"

    Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform

    Journal: STAR Protocols

    doi: 10.1016/j.xpro.2025.104250


    Figure Legend Snippet:

    Techniques Used: Recombinant, Membrane, Software, Imaging

    Related Articles

    Recombinant:

    Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform
    Article Snippet: Canertinib dihydrochloride , Targetmol , T2501.

    Membrane:

    Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform
    Article Snippet: Canertinib dihydrochloride , Targetmol , T2501.

    Software:

    Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform
    Article Snippet: Canertinib dihydrochloride , Targetmol , T2501.

    Imaging:

    Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform
    Article Snippet: Canertinib dihydrochloride , Targetmol , T2501.



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    Image Search Results


    Journal: STAR Protocols

    Article Title: Protocol for high-content drug screening using tumor organoids on a 384-pillar plate platform

    doi: 10.1016/j.xpro.2025.104250

    Figure Lengend Snippet:

    Article Snippet: Canertinib dihydrochloride , Targetmol , T2501.

    Techniques: Recombinant, Membrane, Software, Imaging

    (A) The relative mRNA expressions of Jun and Egfr are shown at each time point. Normalized by Gapdh . (B) Western blots of phosphorylated EGFR and EGFR from the Control and EGFRi groups. (C) The ratio of signal values for phosphorylated EGFR and EGFR in Western blots, normalized by GAPDH. (D) Serum ALT for the Control and EGFRi groups. (E) Immunofluorescence staining of cyclinD1 in EGFR inhibition experiment. GFP, cyclinD1. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of cyclinD1 positivity. (F) Western blot analysis of phosphorylated c-jun and c-jun in the Control and JNKi groups. (G) The ratio of signal values for phosphorylated c-jun and c-jun in Western blots, normalized by GAPDH. (H) Serum ALT for the Control and JNKi groups. (I) Immunofluorescence staining of cyclinD1 in JNK inhibition experiment. GFP, cyclinD1. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of cyclinD1 positivity. (J) Serum ALT for the Control and mTORi groups. (K) Immunofluorescence staining of cyclinD1 in mTOR inhibition experiment. GFP, cyclinD1. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of cyclinD1 positivity.

    Journal: bioRxiv

    Article Title: Two types of regeneration mechanism in acute liver injury

    doi: 10.1101/2024.08.04.606468

    Figure Lengend Snippet: (A) The relative mRNA expressions of Jun and Egfr are shown at each time point. Normalized by Gapdh . (B) Western blots of phosphorylated EGFR and EGFR from the Control and EGFRi groups. (C) The ratio of signal values for phosphorylated EGFR and EGFR in Western blots, normalized by GAPDH. (D) Serum ALT for the Control and EGFRi groups. (E) Immunofluorescence staining of cyclinD1 in EGFR inhibition experiment. GFP, cyclinD1. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of cyclinD1 positivity. (F) Western blot analysis of phosphorylated c-jun and c-jun in the Control and JNKi groups. (G) The ratio of signal values for phosphorylated c-jun and c-jun in Western blots, normalized by GAPDH. (H) Serum ALT for the Control and JNKi groups. (I) Immunofluorescence staining of cyclinD1 in JNK inhibition experiment. GFP, cyclinD1. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of cyclinD1 positivity. (J) Serum ALT for the Control and mTORi groups. (K) Immunofluorescence staining of cyclinD1 in mTOR inhibition experiment. GFP, cyclinD1. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of cyclinD1 positivity.

    Article Snippet: For EGFR inhibition experiments, canertinib dihydrochloride (80 mg/kg, i.p.) (Selleck Chemicals, Tokyo, Japan; # S0711) was dissolved in PBS.

    Techniques: Western Blot, Control, Immunofluorescence, Staining, Inhibition

    (A) Immunofluorescence staining of Ki67 in an EGFR inhibition experiment. TxRed, Ki67. Blue, DAPI. The scale bar is 50μm. The bars represent the percentage of Ki67 positivity. (B) Relative mRNA expression of Jun , normalized by Gapdh . (C) Immunofluorescence staining of Ki67 in the JNK inhibition experiment. TxRed, Ki67. Blue, DAPI. The scale bar is 50μm. The bars represent the percentage of Ki67 positivity. (D) Relative mRNA expression of Egfr , normalized by Gapdh . (E) Immunofluorescence staining of Ki67 during the mTOR inhibition experiment. TxRed, Ki67. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of Ki67 positivity. (F) Immunofluorescence staining for c-jun in the mTOR inhibition experiment. The arrowheads indicate representative positive cells in non-INTR cells. TxRed, c-jun. Blue, DAPI. The scale bar is 50 μm. Bars indicate the positivity rate of c-jun in non-INTR cells. (G) Ridge plot comparing DAPI intensity of non-INTR cell nuclei in the control and mTORi groups.

    Journal: bioRxiv

    Article Title: Two types of regeneration mechanism in acute liver injury

    doi: 10.1101/2024.08.04.606468

    Figure Lengend Snippet: (A) Immunofluorescence staining of Ki67 in an EGFR inhibition experiment. TxRed, Ki67. Blue, DAPI. The scale bar is 50μm. The bars represent the percentage of Ki67 positivity. (B) Relative mRNA expression of Jun , normalized by Gapdh . (C) Immunofluorescence staining of Ki67 in the JNK inhibition experiment. TxRed, Ki67. Blue, DAPI. The scale bar is 50μm. The bars represent the percentage of Ki67 positivity. (D) Relative mRNA expression of Egfr , normalized by Gapdh . (E) Immunofluorescence staining of Ki67 during the mTOR inhibition experiment. TxRed, Ki67. Blue, DAPI. The scale bar is 50 μm. The bars represent the percentage of Ki67 positivity. (F) Immunofluorescence staining for c-jun in the mTOR inhibition experiment. The arrowheads indicate representative positive cells in non-INTR cells. TxRed, c-jun. Blue, DAPI. The scale bar is 50 μm. Bars indicate the positivity rate of c-jun in non-INTR cells. (G) Ridge plot comparing DAPI intensity of non-INTR cell nuclei in the control and mTORi groups.

    Article Snippet: For EGFR inhibition experiments, canertinib dihydrochloride (80 mg/kg, i.p.) (Selleck Chemicals, Tokyo, Japan; # S0711) was dissolved in PBS.

    Techniques: Immunofluorescence, Staining, Inhibition, Expressing, Control